System and method for initiating and maintaining continuous, long-term control of a concentration of a substance in a patient using a feedback or model-based controller coupled to a single-needle or multi-needle intradermal (ID) delivery device

US7060059B2 · kind B2 · utility

Assignee

• Becton, Dickinson and Company · US

Inventors

• Steven Keith · Chapel Hill, US
• Robert Parker · Dryden, US
• Noel G. Harvey · Efland, US
• Ronald J. Pettis · Durham, US
• John D. DeNuzzio · Chapel Hill, US
• Glenn P. Vonk · Fuquay-Varina, US

Key dates

• Filing date: Oct 14, 2003
• Grant date: Jun 13, 2006
• Expiry date: Oct 14, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61M2230/201
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A closed loop therapy system for controlling a concentration of a substance, such as blood glucose concentration, in the body of a user. The system and method employ a sensor system that measures a glucose level in the body, a controller that uses the measured glucose levels to generate an output that can be used to automatically or manually control an intradermal insulin infusion system to set a constant or time-varying profile of target blood glucose concentrations in a user, and then infuse an appropriate amount of insulin into the body of the user so as to reach and maintain the target values of the blood glucose concentration.