Death domain containing receptor-4 agonist antibodies and methods
US7060272B2 · kind B2 · utility
9Cited by
4References
220Claims
0Family size
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Key dates
| Filing date | Aug 23, 2002 |
| Grant date | Jun 13, 2006 |
| Priority date | — |
| Expiry date | Jun 8, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/70578
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention relates to novel Death Domain Containing Receptor-4 (DR4) proteins which are members of the tumor necrosis factor (TNF) receptor family. In particular, isolated nucleic acid molecules are provided encoding the human DR4 proteins. DR4 polypeptides are also provided as are vectors, host cells and recombinant methods for producing the same. The invention further relates to screening methods for identifying agonists and antagonists of DR4 activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.