Method of preparing GALR2 receptors composition

US7060449B2 · kind B2 · utility

Assignee

• H. LUNDBECK A/S · DK

Inventors

• Kelli E. Smith · Wayne, US
• Christophe P. G. Gerald · Ridgewood, US
• Richard L. Weinshank · Teaneck, US
• David L. Linemeyer · Guilford, US
• Theresa Branchek · Teaneck, US
• Carlos Forray · Paramus, US

Key dates

• Filing date: Nov 18, 2002
• Grant date: Jun 13, 2006
• Expiry date: Dec 1, 2024

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K48/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

This invention provides isolated nucleic acids encoding mammalian galanin receptors, isolated galanin receptor proteins, vectors comprising isolated nucleic acid encoding a mammalian galanin receptor, cells comprising such vectors, antibodies directed to a mammalian galanin receptor, nucleic acid probes useful for detecting nucleic acid encoding a mammalian galanin receptor, antisense oligonucleotides complementary to unique sequences of nucleic acid encoding a mammalian galanin receptor, nonhuman transgenic animals which express DNA encoding a normal or a mutant mammalian galanin receptor, as well as methods of determining binding of compounds to mammalian galanin receptors.