Stereoselective antifibrillogenic peptides and peptidomimetics thereof
US7060670B1 · kind B1 · utility
3Cited by
24References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 4, 2000 |
| Grant date | Jun 13, 2006 |
| Priority date | — |
| Expiry date | May 4, 2020 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to antifibrillogenic agents for inhibiting amyloidosis and/or for cytoprotection for the treatment amyloidosis disorders. These agents include peptides, isomers thereof and peptidomimetic compounds thereof. These agents comprise peptide having a sequence identified from the glycosaminoglycan (GAG) binding region and the prot—prot interaction region of the amylo protein. The peptide has at least one [D] amino acid isomer substitution. The invention also relates to the peptide bound to a label for vivo imaging of amyloid deposits.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.