Use of antimicrobial proteins and peptides for the treatment of otitis media and paranasal sinusitis
US7060674B2 · kind B2 · utility
7Cited by
5References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 6, 2004 |
| Grant date | Jun 13, 2006 |
| Priority date | — |
| Expiry date | Apr 6, 2024 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/47
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Disclosed herein is a composition and a method for the treatment of otitis media and paranasal sinusitis using human defensins, lysozyme and/or lactoferrin as a new class of non-antibiotic antimicrobials. From studies of otitis media and paranasal sinusitis, it was observed that certain innate immune modulators were important in the bodies response to the infection. Therefore, these innate immune modulators, lysozyme, lactoferrin, and defensins were tested for use as a non-antibiotic treatment for infection, particularly infections such as otitis media and sinusitis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.