Stabilized activated derivatives of carbamic acid, their process of preparation and their use for the preparation of ureas
US7060845B2 · kind B2 · utility
8Cited by
4References
13Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Jul 16, 2001 |
| Grant date | Jun 13, 2006 |
| Priority date | — |
| Expiry date | Oct 16, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G71/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Process for the preparation of stable activated derivatives of carbamic acid, comprising at least one protected amino group and an activated carbamic acid function, from an amino acid derivative in which the amino group is protected. The process includes: a) a step of transformation of the —COOH group of the amino acid derivative into a —CON3 group to obtain an acyl azide; b) a step of transformation of the —CON3 group of the acyl azide into a —NCO group to obtain an isocyanate; c) a step of treating the isocyanate to obtain a stable derivative of carbamic acid.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.