Antigen-specific, activated T lymphocytes, detection and use

US7064190B1 · kind B1 · utility

Assignee

• Roche Diagnostics GMBH · DE

Inventors

• Josef Endl · Weilheim, DE
• Peter Stahl · New York, US
• Winfried Albert · Eberfing, DE
• Guenther-Gerhard Jung · Tübingen, DE
• Dolores Schendel · Munich, DE
• Edgar Meinl · Krailling, DE
• Klaus Dornmair · Palo Alto, US

Key dates

• Filing date: Nov 16, 1999
• Grant date: Jun 20, 2006
• Expiry date: Nov 16, 2019

Classification

• Technology area (CPC G): Physics
• CPC primary: G01N33/56977
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The invention concerns autoreactive peptides, peptide-MHC complexes, T cell subpopulations that react thereto as well as diagnostic and therapeutic applications of these compounds.