Patent · US Expired

Liquid chromatograph and analysis system

US7066011B2 · kind B2 · utility

4Cited by
19References
9Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 8, 2001
Grant dateJun 27, 2006
Priority date
Expiry dateApr 8, 2021

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N30/7233
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

The present invention aims to provide a liquid chromatograph, an analysis system, and a gradient elution method, which are designed to permit a gradient change of eluent with higher precision and also permit a high sensitive detection or analysis. For attaining the object, there are provided: a liquid chromatograph having at least a liquid-feeding means for flowing an eluent E at a predetermined flow rate, a sample-pouring means for pouring a sample Sm into the eluent E, and a separation-column means for separating a solute So contained in the sample Sm into components, comprising an eluent-selecting means for forming branched flow paths having predetermined volumes by dividing a flow path of the eluent E fed from the liquid-feeding means, temporally storing eluents E1, E2, and soon in the branched flow paths, and pouring the sample Sm into the selected eluents E1, E2, and so on, and means for carrying out a gradient elution of a solute So; an analysis system comprising a mass spectrometer connected to the liquid chromatograph, and a gradient-elution method using the liquid chromatograph.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.