Premixed amiodarone parenteral solution and method for making the same
US7067143B2 · kind B2 · utility
2Cited by
3References
29Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 31, 2001 |
| Grant date | Jun 27, 2006 |
| Priority date | — |
| Expiry date | Aug 31, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P9/06
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A premix parenteral solution for intravenous administration having amiodarone, as an active ingredient, solubilized in a solution of water for injection and about 0.4-12 mg/ml of a non-ionic surfactant to a concentration range of from 0.2 to 6 mg/ml is disclosed. The solution optionally may include an osmotic agent. No dilution of the solution is required before administering to a patient and the sterile packaged solution has an initial pH within the range of from about 2.9 to about 3.2, preferably about 3.1. Additionally, a method for producing an amiodarone solution suitable for intravenous administration is further disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.