Patent · US Expired

Compounds useful for inhibiting Chk1

US7067506B2 · kind B2 · utility

17Cited by
4References
25Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 1, 2002
Grant dateJun 27, 2006
Priority date
Expiry dateApr 28, 2023

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D453/02
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Aryl- and heteroaryl-substituted urea compounds useful in the treatment of diseases and conditions related to DNA damage or lesions in DNA replication are disclosed. Methods of making the compounds, and their use as therapeutic agents, for example, in treating cancer and other diseases characterized by defects in DNA replication, chromosome segregation, or cell division also are disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.