Patent · US Expired

Substituted 1,4-benzodiazepines and uses thereof

US7067512B2 · kind B2 · utility

3Cited by

9References

33Claims

0Family size

Inventors

Tianbao Lu · Collegeville, US
Louis Lafrance · Collegeville, US
Daniel Parks · Linglestown, US
Karen L. Milkiewicz · Exton, US
Raul Calvo · Royersford, US
Maxwell D. Cummings · Strafford, US
Alexander Kim · Levittown, US
Bruce Grasberger · Trappe, US
Theodore Carver · Downingtown, US

Key dates

Filing date	Nov 13, 2002
Grant date	Jun 27, 2006
Priority date	—
Expiry date	Nov 13, 2023

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D409/04
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The present invention is directed to novel 1,4-benzodiazepines, pharmaceutical compositions thereof, and the use thereof as inhibitors of HDM2-p53 interactions. Compounds have Formula I:or a solvate, hydrate or pharmaceutically acceptable salt thereof; wherein:

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.