28-epirapalogs
US7067526B1 · kind B1 · utility
10Cited by
44References
42Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 24, 2000 |
| Grant date | Jun 27, 2006 |
| Priority date | — |
| Expiry date | Aug 24, 2020 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Rapamycin derivatives containing substituents at C-28 in the epi orientation relative to rapamycin are disclosed, together with methods for their preparation and use, e.g. for regulation of biological phenomena in engineered cells. The compounds may contain optional additional modifications relative to rapamycin, as disclosed herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.