Substituted anilinic piperidines as MCH selective antagonists

US7067534B1 · kind B1 · utility

Assignee

• H. LUNDBECK A/S · DK

Inventors

• Mohammad R. Marzabadi · Ridgewood, US
• John Wetzel · Elmwood Park, US
• John E. DeLeon · North Bergen, US
• Yu Jiang · Plainsboro, US
• Chien-An Chen · Madison, US
• Kai Lu · Elmwood Park, US

Key dates

• Filing date: Nov 21, 2003
• Grant date: Jun 27, 2006
• Expiry date: Dec 24, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D495/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

This invention is directed to compounds which are selective antagonists for melanin concentrating hormone-1 (MCH1) receptors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier. This invention provides a pharmaceutical composition made by combining a therapeutically effective amount of the compound of this invention and a pharmaceutically acceptable carrier. This invention further provides a process for making a pharmaceutical composition comprising combining a therapeutically effective amount of the compound of the invention and a pharmaceutically acceptable carrier.