Patent · US Expired

4-,6- or 7-hydroxyindoles with N-oxide groups and the use thereof as therapeutic agents

US7067536B2 · kind B2 · utility

2Cited by

3References

7Claims

0Family size

Assignee

elbion GmbH · DE

Inventors

Nobert Hofgen · Radeberg, DE
Hildegard Kuss · Dresden, DE
Karin Steinike · Radebeul, DE
Ute Egerland · Radebeul, DE
Chris Rundfeldt · Coswig, DE

Key dates

Filing date	Apr 16, 2004
Grant date	Jun 27, 2006
Priority date	—
Expiry date	May 11, 2024

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The invention relates to substituted 4-, 6- or 7-hydroxyindoles with N-oxide groups, process for their preparation, pharmaceutical preparations which comprise these compounds, and the pharmaceutical use of these compounds, which are inhibitors of phosphodiesterase 4, as active ingredients for the treatment of disorders which can be influenced by inhibition of phosphodiesterase 4 activity in particular in immunocompetent cells (e.g. macrophages and lymphocytes) by the compounds of the invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.