Regulatory sequences of the mouse villin gene—use in transgenesis
US7067648B2 · kind B2 · utility
Assignees
Inventors
Key dates
| Filing date | Jun 8, 2001 |
| Grant date | Jun 27, 2006 |
| Priority date | — |
| Expiry date | Jun 8, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/44
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention relates to regulatory sequences of the mouse villin gene that efficiently drive transgenic expression in immature and differentiated epithelial cells of the intestine and uro-genital tracts. The invention also relates to recombinant constructs comprising said regulatory sequences, for the control of the targeted expression of determined nucleic acid sequences so-called (heterologous sequences or also transgenes), in cells or tissues originating from the intestinal mucosa. A further object of the invention is to provide cells, tissues or organisms including animals, expressing said determined nucleic acid sequences in a targeted manner.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.