Bi-directional synthesis of oligoguanidine transport agents
US7067698B2 · kind B2 · utility
3Cited by
16References
30Claims
0Family size
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Key dates
| Filing date | Aug 2, 2002 |
| Grant date | Jun 27, 2006 |
| Priority date | — |
| Expiry date | Apr 3, 2023 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K1/006
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Synthesis routes that can be adapted to large scale synthesis of oligoguanidine compounds such as oligoarginine compounds are described which use a perguanidinylation step to convert a group of ω-amino groups to the corresponding guanidinyl groups. These compounds find utility as transport agents. Modified oligoguanidine compounds are also described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.