Combinational usage of insulators and coat color marker for high efficiency transgene expression and visual genotyping in mice
US7067715B2 · kind B2 · utility
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14Claims
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Key dates
| Filing date | Nov 3, 2003 |
| Grant date | Jun 27, 2006 |
| Priority date | — |
| Expiry date | Nov 3, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K67/0275
- WIPO fieldOther special machines
- WIPO sectorMechanical engineering
Abstract
A method of identifying a genotype of a transgenic mouse and reducing the variability of a transagene expression in the transgenic mouse comprises the step of introducing into a mouse (a) a transgene expression cassette, (b) a coat color expression cassette and (c) an insulator positioned at 5′ or 3′ end of the transgene expression cassette.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.