Retroviral vectors with foreign-sequence insertion between retroviral primer binding site and retroviral splice donor
US7070992B2 · kind B2 · utility
3Cited by
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54Claims
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Key dates
| Filing date | Sep 10, 2001 |
| Grant date | Jul 4, 2006 |
| Priority date | — |
| Expiry date | Sep 10, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/203
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject of the invention is retroviral gene transfer vectors in which foreign sequences are introduced between the retroviral primer binding site (PBS) and the retroviral splice donor (SD). The efficiency of gene expression is improved by this modification, and the vectors are characterized by an increased reliability during use.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.