Anti-cancer compounds and methods related thereto

US7071168B2 · kind B2 · utility

Assignee

• The Regents of the University of Colorado · US

Inventors

• John M. Stewart · Lawrence, US
• Daniel Chan · Denver, US
• Lajos Gera · Denver, US
• Eunice York · Englewood, US
• Paul Bunn · Evergreen, US

Key dates

• Filing date: Dec 28, 2001
• Grant date: Jul 4, 2006
• Expiry date: Jun 21, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S530/816
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention provides compounds useful to inhibit tumor growth and to induce apoptosis. In general, the anti-cancer agents (ACA) are described by the formula:[ACA]n-X[Formula I]wherein X is a linker group having 2–5 functional groups or is absent, n=1, and ACA is selected from the group consisting of Formula II, Formula III, Formula IV, Formula V, and Formula VI, as described herein. Other compounds described herein are defined by the Formula VII, as described herein.