Latent reactive blood compatible agents
US7071235B2 · kind B2 · utility
4Cited by
13References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 24, 2003 |
| Grant date | Jul 4, 2006 |
| Priority date | — |
| Expiry date | Apr 24, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L33/0082
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A reagent and related method for use in passivating a biomaterial surface, the reagent including a latent reactive group and a bifunctional aliphatic acid (e.g., fatty acid), in combination with a spacer group linking the latent reactive group to the aliphatic acid in a manner that preserves the desired function of each group. Once bound to the surface, via the latent reactive group, the reagent presents the aliphatic acid to the physiological environment, in vivo, in a manner (e.g., concentration and orientation) sufficient to hold and orient albumin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.