Signal for targeting molecules to the sarco(endo)plasmic reticulum
US7071295B2 · kind B2 · utility
28Cited by
0References
20Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 29, 2003 |
| Grant date | Jul 4, 2006 |
| Priority date | — |
| Expiry date | May 25, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to targeting molecules to subcellular locations. In particular, the invention relates to compositions and methods to target molecules to the sarco(endo)plasmic reticulum (SR). The invention includes uses for polypeptide sequences as a localization signal to target therapeutic and experimental compounds or macromolecules to the SR of eukaryotic cells. The invention also includes nucleotide sequences encoding the polypeptide SR localization signal, allowing it to be incorporated into vectors for delivery of therapeutic or experimental gene products via in vitro or in vivo gene transfer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.