Transgenic ungulate compositions and methods
US7071373B1 · kind B1 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 24, 1995 |
| Grant date | Jul 4, 2006 |
| Priority date | — |
| Expiry date | Mar 24, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Transgenic ungulates and compositions and methods for making and using same, are provided. Central to the invention are porcine, bovine, ovine and caprine embryonic stem cell lines and methods for establishing them. Cells of such lines are transformed with exogenous genetic material of interest and then used to provide chimeric ungulates confirmed by genetic markers which have germ cells comprising the exogenous genetic material. The chimeric ungulates are bred to provide transgenic ungulates. The transgenic animals of the invention may show improved qualities and can be used to provide human proteins or peptide hormones or can be used as xenograft donors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.