α-β C4BP-type recombinant heteromultimeric proteins

US7074411B1 · kind B1 · utility

Assignees

• Universite Pierre Et Marie Curie (Paris 6) · FR
• UNIVERSITÉ DE REIMS CHAMPAGNE-ARDENNE · FR

Inventors

• David Klatzmann · Paris, FR
• Jacques Cohen · New York, US

Key dates

• Filing date: Jul 18, 1996
• Grant date: Jul 11, 2006
• Expiry date: Jul 18, 2016

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/81
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A recombinant heteromultimeric protein including at least (a) a polypeptide fusion molecule A consisting of a C4BP α-chain C-terminal fragment and a polypeptide fragment heterologous to said α-chain, and (a) a polypeptide fusion molecule B consisting of a C4BP β-chain C-terminal fragment and a polypeptide fragment heterologous to said β-chain, wherein (a) and (b) are linked in the C-terminal portion to form said multimeric protein.