Mycobacterial diagnostics

US7074559B2 · kind B2 · utility

Assignees

• Regents of the University of Minnesota · US
• The Unites States of America, as represented by the Secretary of Agriculture · US

Inventors

• Vivek Kapur · Kennett Square, US
• John P. Bannantine · Ames, US
• Ling-Ling Li · Arden Hills, US
• Qing Zhang · Seattle, US
• Alongkorn Amonsin · Lopburi, TH

Key dates

• Filing date: Apr 30, 2002
• Grant date: Jul 11, 2006
• Expiry date: Oct 26, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12Q2600/16
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention provides nucleic acid molecules unique to M. paratuberculosis. The invention also provides the polypeptides encoded by the M. paratuberculosis-specific nucleic acid molecules of the invention, and antibodies having specific binding affinity for the polypeptides encoded by the M. paratuberculosis-specific nucleic acid molecules. The invention further provides for methods of detecting M. paratuberculosis in a sample using nucleic acid molecules, polypeptides, and antibodies of the invention. The invention additionally provides methods of preventing a M. paratuberculosis infection in an animal.