Asthma associated factors as targets for treating atopic allergies including asthma and related disorders
US7074778B2 · kind B2 · utility
3Cited by
14References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 11, 2000 |
| Grant date | Jul 11, 2006 |
| Priority date | — |
| Expiry date | May 30, 2021 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to methods for treating asthma or allergy in a mammal by administering a 3-aminosteroid compound to a mammal in need thereof. The 3-aminosteroid compound being capable of down regulating the IL-9 pathway and alleviating asthmatic responses to allergen. Exemplary 3-aminosteroid compounds used in the methods of the invention include compounds having the chemical formula (I), wherein X, R1, R2, R3, and R4 groups are as defined herein. The invention also relates to certain novel compounds of formula (I). Moreover, the invention also provides methods for identifying an immunomodulatory 3-aminosteroid compound.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.