Alkyl carbamate-substituted β-lactones, process for their preparation, and pharmaceutical compositions containing them

US7074822B2 · kind B2 · utility

Assignee

• Solvay Pharmaceuticals, GmbH · US

Inventors

• Jochen Antel · Annaberg-Buchholz, DE
• Sabine Eyting · Munster, DE
• Peter-Colin Gregory · Hannover, DE
• Harald Waldeck · Hannover, DE
• Michael Wurl · Garbsen, DE
• Maike Wolff · Hannover, DE

Key dates

• Filing date: Feb 22, 2005
• Grant date: Jul 11, 2006
• Expiry date: Mar 4, 2025

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D305/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Substituted β-lactones (oxetanones) corresponding to the formula I,wherein R1, R2 and n have the meanings given in the specification, and pharmaceutical compositions which contain these compounds and have a pancreatic lipase-inhibiting action, as well as a process for the preparation of the compounds of Formula I and intermediate products of this process.