Oncolytic adenovirus
US7078030B2 · kind B2 · utility
10Cited by
0References
9Claims
0Family size
Assignee
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Key dates
| Filing date | Dec 11, 2003 |
| Grant date | Jul 18, 2006 |
| Priority date | — |
| Expiry date | Jun 6, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/008
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Viral vectors and methods of making such vectors are described that preferentially kill neoplastic but not normal cells, the preferred vector being an adenovirus that has the endogenous promoters in the E1A and/or E4 regions substituted with a tumor specific promoter which is preferably E2F responsive.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.