Patent · US Expired

Production of polyketides in bacteria and yeast

US7078233B2 · kind B2 · utility

4Cited by
11References
11Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 8, 2001
Grant dateJul 18, 2006
Priority date
Expiry dateMay 8, 2021

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K2319/00
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Hybrid and novel polyketide synthases and polyketides are produced by use of a multiple vector system. The combinatorial possibilities offered by placing the various catalytic activities of PKS systems on separate vectors permits the construction of improved libraries of PKS and polyketides. In addition, polyketides can be produced in hosts that ordinarily do not produce polyketides by supplying, along with an expression system for the desired PKS, an expression system for holo ACP synthase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.