Patent · US Expired

Aryl substituted pyrazoles, triazoles, and tetrazoles, and the use thereof

US7078426B2 · kind B2 · utility

44Cited by

14References

21Claims

0Family size

Assignee

Euro-Celtique S.A. · LU

Inventors

Derk Hogenkamp · Carlsbad, US
Phong X. Nguyen · Placentia, US
Ji Yang · Jingwei, CN

Key dates

Filing date	Mar 22, 2001
Grant date	Jul 18, 2006
Priority date	—
Expiry date	Mar 8, 2024

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D249/08
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Het and R5-R8 are set in the specification. The invention also is directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.