Process to bromomethylate aromatic compounds
US7078465B2 · kind B2 · utility
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25Claims
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Key dates
| Filing date | Aug 29, 2001 |
| Grant date | Jul 18, 2006 |
| Priority date | — |
| Expiry date | Oct 3, 2021 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2527/138
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a process for bromomethylation of organic compounds, wherein said process is a two stage process comprising of the following stages: a) reacting paraformaldehyde with hydrogen bromide and separating bis-bromomethyl ether (BBME) from the reaction mixture, and, b) reacting BBME obtained in stage (a) with an organic compound in the presence of a Lewis acid, to obtain the bromomethylated organic compound. Further provided by the present invention is a process for the preparation of 4,4′-bis-(diethylphosphonomethyl)-biphenyl (BPMB).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.