Patent · US Expired

Sodium-channel alpha1-subunit and their polypeptides and their treatment of generalized epilepsy with febrile seizures plus

US7078515B2 · kind B2 · utility

10Cited by

0References

20Claims

0Family size

Assignee

Bionomics Limited · AU

Inventors

Robyn Heather Wallace · Brisbane, AU
John Charles Mulley · Adelaide, AU
Samuel Frank Berkovic · Melbourne, AU

Key dates

Filing date	Dec 20, 2001
Grant date	Jul 18, 2006
Priority date	—
Expiry date	Feb 28, 2022

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61K2039/505
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

The mutations D188V, V1353L, I1656M in the neuronal gene sodium-channel alpha1-subunit, SCN1A, are disclosed. The methods of using their associated polypeptides for treating sodium channel dysfunction disorders including generalized epilepsy are also disclosed.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.