Charged compounds comprising a nucleic acid binding moiety and uses therefor

US7078536B2 · kind B2 · utility

Assignee

• Genesoft Pharmaceuticals, Inc. · US

Inventors

• Yigong Ge · Mill Valley, US
• Matthew Taylor · Cincinnati, US
• Eldon E. Baird · Pasadena, US
• Heinz Ernst Moser · San Mateo, US
• Roland Burli · Pasadena, US

Key dates

• Filing date: Oct 22, 2002
• Grant date: Jul 18, 2006
• Expiry date: Sep 17, 2023

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Charged compounds are provided that comprise one or more regions of localized positive charge, compositions comprising such compounds, methods of synthesizing such compounds, methods of screening such compounds to identify those having anti-infective activity, and methods of using such compounds to prevent or inhibit infections. These compounds, and compositions containing them, have multiple applications, including use in human and animal medicine and in agriculture.