Silanyl phenols and naphthols

US7078550B2 · kind B2 · utility

Assignee

• Ciba Specialty Chemicals Corporation · US

Inventors

• Werner Hölzl · Eschentzwiller, FR
• Wolfgang Haap · Bad Kötzting, DE
• Jurgen Koppold · Lörrach, DE

Key dates

• Filing date: Jan 10, 2002
• Grant date: Jul 18, 2006
• Expiry date: Mar 26, 2022

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/081
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are described silanyl phenols and naphthols of formula (1a) or (1b), wherein R1 is hydrogen; halogen; hydroxy; C1–C20alkyl; C3–C12cycloalkyl; C1–C20alkoxy; trifluoromethyl; pentafluoroethyl; mono- or di-C1–C5alkylamino; hydroxy-C1–C5alkyl; or phenyl, phenyl-C1–C20alkyl, phenoxy, phenyl-C1–C20alkoxy, naphthyl or naphthyl-C1–C20alkyl each unsubstituted or substituted by C1–C5alkyl, C3–C12cycloalkyl, C1–C5alkoxy, C3–C12cycloalkoxy, halogen, oxo, carboxy, carboxy-C1–C7alkyl ester, carboxy-C3–C12cycloalkyl ester, cyano, trifluoromethyl, pentafluoroethyl, amino, N,N-mono- or di-C1–C20alkylamino or by nitro; R2, R3 and R4 are each independently of the others hydrogen; C1–C20alkyl; or C3–C12-cycloalkyl; R5, R6 and R7 are each independently of the others C1–C20alkyl, C5–C10aryl, C1–C20alkoxy, phenyl-C1–C20alkyl, phenyl-C1–C20alkoxy, C2–C5alkenyl, —O—Si—(C1–C5alkyl)3; or O—Si—(C1–C5alkyl)2-O—Si(C1–C5alkyl)3 and n is 0 or 1. The compounds exhibit a pronounced activity against Gram positive and Gram negative bacteria, and also against yeasts and moulds