Process for the preparation of ωbenzyl esters of amino diacids and of alkanesulphonates of these esters, and these alkanesulphonates
US7078564B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Dec 17, 2003 |
| Grant date | Jul 18, 2006 |
| Priority date | — |
| Expiry date | Jan 28, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C229/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to a process for the preparation of an ω-benzyl ester of an amino diacid, characterized in that the amino diacid is reacted with a benzyl alcohol derivative of formula (I) in which the R1 substituent or substituents, which are identical or different, represent a hydrogen atom, a C1 to C4 alkyl group, a C1 to C4 alkoxy group or a halogen atom and n is equal to 1, 2 or 3, in the presence of at least one mol per mole of the amino diacid of an alkanesulphonic acid, optionally in the presence of a solvent.The intermediate alkanesulphonates of the ω-benzyl esters of amino diacids and the ω-benzyl esters of amino diacids are obtained with a good yield and an excellent purity by virtue of this process.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.