Preparation of 1,3-di-halo-substituted benzene derivatives

US7078571B2 · kind B2 · utility

Assignee

• Clariant Corporation · DE

Inventors

• Stefan Brand · Leutershausen, DE
• Daniel Decker · Castle Rock, US
• Thomas Wessel · Frankfurt, DE

Key dates

• Filing date: Oct 24, 2003
• Grant date: Jul 18, 2006
• Expiry date: Apr 28, 2024

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C17/361
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for preparing 1,3-di-halo-substituted benzene derivatives (II) from 2,6-di-halo-substituted benzaldehydes (I) (where X1, X2 are each independently F, Cl, Br, and R1, R2, R3 are each independently H, halogen, OH, C1–C12-alkyl, CF3, CHO, C6–C14-aryl, Oalkyl, Oaryl, NO2) by reacting with an alkaline medium, which comprises initially charging the alkaline medium and metering in the 2,6-di-halo-substituted benzaldehyde (I) or initially charging the 2,6-di-halo-substituted benzaldehyde (I) and metering in the alkaline medium