Methods for identifying modulators of NF-KB activity

US7081343B2 · kind B2 · utility

Assignee

• The Regents of the University of California · US

Inventors

• Lin Chen · Champaign, US
• Wolfgang Fischle · Charlottesville, US
• Eric Verdin · San Francisco, US
• Warner C. Greene · Chapel Hill, US

Key dates

• Filing date: Jun 18, 2001
• Grant date: Jul 25, 2006
• Expiry date: Sep 11, 2021

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07K14/4702
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The present invention provides methods for identification of agents that modulate NF-κB activity through modulation of the acetylation and deacetylation of the RelA subunit of NF-κB.