Method and means for producing high titer, safe, recombinant lentivirus vectors
US7083981B2 · kind B2 · utility
9Cited by
20References
14Claims
0Family size
Assignee
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Key dates
| Filing date | Jul 21, 2005 |
| Grant date | Aug 1, 2006 |
| Priority date | — |
| Expiry date | Jul 21, 2025 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16052
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Lentiviral vectors modified at the 5′ LTR or both the 5′ and 3′ LTR's are useful in the production of recombinant lentivirus vectors. Such vectors can be produced in the absence of a functional tat gene. Multiple transformation of the host cell with the vector carrying the transgene enhances virus production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.