Prodrugs of DP IV-inhibitors

US7084120B2 · kind B2 · utility

Assignee

• PROBIODRUG AG · DE

Inventors

• Hans-Ulrich Demuth · Halle (Saale), DE
• Dagmar Schlenzig · Bodenwerder, DE
• Torsten Hoffmann · Weil am Rhein, DE
• Susanne Manhart · Halle (Saale), DE

Key dates

• Filing date: Dec 22, 2000
• Grant date: Aug 1, 2006
• Expiry date: Dec 17, 2023

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Prodrug compounds of unstable inhibitors of the serine peptidase dipeptidyl peptidase IV, are used in the treatment of various disorders, especially of metabolic disorders. The Prodrug compounds can be used in the treatment of impaired glucose tolerance, glucosuria, hyperlipidaemia, metabolic acidoses, diabetes mellitus, diabetic neuropathy and nephropathy.