Patent · US Expired

Heterocyclic inhibitors of kinases

US7084160B2 · kind B2 · utility

3Cited by
3References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 18, 2003
Grant dateAug 1, 2006
Priority date
Expiry dateJul 10, 2024

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D417/14
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

The present invention provides compounds of formula Iand pharmaceutically acceptable salts thereof.The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2, FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.