Patent · US Expired

Compounds and therapies for the prevention of vascular and non-vascular pathologies

US7084171B2 · kind B2 · utility

29Cited by
96References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateApr 19, 2004
Grant dateAug 1, 2006
Priority date
Expiry dateApr 19, 2024

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N2800/323
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The invention provides a method of treating a mammal having, or at risk of, an indication associated with a TGF-beta deficiency comprising administering one or more agents that is effective to elevate the level of TGF-beta. The invention also provides novel compounds that elevate TGF-beta levels, as well as pharmaceutical compositions comprising compounds that elevate TGF-beta levels, and methods for detecting diseases associated with endothelial cell activation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.