Glucopyranosyloxypyrazole derivatives and medicinal use thereof
US7087579B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Feb 26, 2002 |
| Grant date | Aug 8, 2006 |
| Priority date | — |
| Expiry date | Feb 26, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H17/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides glucopyranosyloxypyrazole derivatives represented by the general formula:wherein one of Q and T represents a group represented by the general formula:while the other represents a lower alkyl group or a halo(lower alkyl) group; R1 represents a hydrogen atom, an optionally substituted lower alkyl group, a lower alkenyl group, a cyclic lower alkyl group, etc.; R2 represents a hydrogen atom, an optionally substituted lower alkyl group, a lower alkoxy group, a lower alkenyl group, a cyclic lower alkyl group, a cyclic lower alkoxy group, etc., which exert an excellent inhibitory activity in human SGLT2, and therefore are useful as drugs for the prevention or treatment of a disease associated with hyperglycemia such as diabetes, diabetic complications or obesity, pharmaceutically acceptable salts thereof or prodrugs thereof, production intermediates thereof and pharmaceutical uses thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.