Pyrimidine 5-carboxamide compounds, process for producing the same and use thereof
US7087597B1 · kind B1 · utility
26Cited by
2References
28Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 11, 2000 |
| Grant date | Aug 8, 2006 |
| Priority date | — |
| Expiry date | Jul 9, 2022 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formulawherein R1, R2, R3, R4, X and Y are as defined, which have a superior cGMP specific phosphodiesterase (PDE) inhibitory activity, and can be used as an agent for the treatment of cardiovascular diseases such as angina pectoris, heart failure, cardiac infarction, hypertension, arteriosclerosis, and the like; allergic diseases such as asthma, or disorders of male or female genital function and the like.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.