Salts of bicyclic, N-acylated imidazo-3-amines and imidazo-5-amines

US7087607B2 · kind B2 · utility

Assignee

• Gruenenthal GmbH · DE

Inventors

• Matthias Gerlach · Wächtersbach, DE
• Corinna Sundermann · Aachen, DE

Key dates

• Filing date: Oct 18, 2002
• Grant date: Aug 8, 2006
• Expiry date: Apr 5, 2023

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D513/04
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Salts of a bicyclic, N-acylated imidazo-3-amine or an imidazo-5-amine of the formula:addition products thereof with acids, and methods for preparing the salts and addition products. Also disclosed are pharmaceutical compositions comprising the same and methods using the pharmaceutical compositions for the treatment or prophylaxis of pain, drug or alcohol abuse, diarrhoea, gastritis, ulcers, urinary incontinence, depression, narcolepsy, overweight, asthma, glaucoma, tinnitus, itching, hyperkinetic syndrome, epilepsy, or schizophrenia, for inducing anesthesia, and for anxiolysis.