Substituted indoles which are PARP inhibitors

US7087637B2 · kind B2 · utility

Assignee

• BASF SE

Inventors

• Roland Grandel · Dossenheim, DE
• Wilfried Lubisch · Mannheim, DE
• Michael Andreas Kock · Schifferstadt, DE
• Thomas Höger · Edingen-Neckarhausen, DE
• Reinhold Müller · Schifferstadt, DE
• Sabine Schult · Speyer, DE
• Uta Holzenkamp · Lambsheim, DE

Key dates

• Filing date: May 9, 2001
• Grant date: Aug 8, 2006
• Expiry date: May 10, 2022

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to novel indole derivatives, to their preparation and to their use, as inhibitors of the enzyme poly(ADP-ribose)polymerase or PARP (EC 2.4.2.30), for producing drugs.