Human paris-1 antigen and nucleic acids: diagnostic and therapeutic uses
US7087715B2 · kind B2 · utility
Assignee
Inventor
Key dates
| Filing date | Mar 13, 2001 |
| Grant date | Aug 8, 2006 |
| Priority date | — |
| Expiry date | Oct 6, 2021 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to the discovery, identification and characterization of a novel tumor suppressor gene designated PARIS-1. The invention includes nucleotide sequences of the PARIS-1 gene and amino acid sequences of its encoded protein product(s), as well as fragments, derivatives and analogs thereof. The invention also includes the production of PARIS-1 proteins, fragments and derivatives and of antibodies specific for PARIS-1 gene products. The invention further comprises agents and compositions which can modulate the expression of PARIS-1 or PARIS-1 expression products to effect the proliferation of cells which express PARIS-1. One particular embodiment comprises agents and compounds which can slow or ablate the proliferation of prostate tumor cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.