External addition of pulses to fluid channels of body to release or suppress endothelial mediators and to determine effectiveness of such intervention
US7090648B2 · kind B2 · utility
97Cited by
4References
156Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 28, 2001 |
| Grant date | Aug 15, 2006 |
| Priority date | — |
| Expiry date | Jul 15, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61N1/326
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
Methods of medical treatment and diagnosis using mediators released by endothelial cells stimulated by external addition of pulses to the circulation are disclosed. The external pulses produce circumferential shear stress in body fluid channels that subsequently stimulates the endothelial cells to produce mediators that become available for therapeutic and diagnostic purposes. The preferred means of adding external pulses is the mechanical inducement of periodic acceleration of the body or parts of the body by a reciprocating motion platform.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.