Compositions and methods for tissue specific targeting of lentivirus vectors
US7090837B2 · kind B2 · utility
22Cited by
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11Claims
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Key dates
| Filing date | Jan 16, 2004 |
| Grant date | Aug 15, 2006 |
| Priority date | — |
| Expiry date | Apr 19, 2024 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2810/855
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This disclosure provides lentiviral vectors containing an attachment incompetent fusogenic polypeptide and a heterologous targeting polypeptide. Also provided are lentiviral packaging constructs, lentiviral packaging systems, and lentiviral gene delivery systems. Finally, methods of transducing a cell and methods of targeting a gene to a cell or tissue using the disclosed lentiviral vectors and systems are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.