P450/acetaminophen genetically directed enzyme prodrug therapy (GDEPT)
US7091040B1 · kind B1 · utility
2Cited by
1References
39Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 30, 1999 |
| Grant date | Aug 15, 2006 |
| Priority date | — |
| Expiry date | Dec 30, 2019 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention hereindescribed relates to a form of cancer therapy which exploits the cytotoxic properties of acetaminophen when converted to NABQI by the metabolic activity of tumour cell specific P450; vectors for use in the delivery of P450 to tumour cells; and therapeutic compositions comprising said vectors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.