Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
US7091181B2 · kind B2 · utility
Assignee
Inventors
Key dates
| Filing date | Apr 20, 2001 |
| Grant date | Aug 15, 2006 |
| Priority date | — |
| Expiry date | May 9, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/17
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method and solution for perioperatively inhibiting a variety of pain and inflammation processes at wounds from general surgical procedures including oral/dental procedures. The solution preferably includes at least one tumor necrosis factor (TNF) soluble receptor at dilute concentration in a physiologic carrier, such as saline or lactated Ringer's solution. The solution is applied locally and perioperatively to a surgical site during a surgical procedure for preemptive inhibition of pain and while avoiding undesirable side effects associated with oral, intramuscular, subcutaneous or intravenous application of larger doses of the agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.