p-Amidobenzylethers in drug delivery agents
US7091186B2 · kind B2 · utility
138Cited by
9References
38Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 24, 2001 |
| Grant date | Aug 15, 2006 |
| Priority date | — |
| Expiry date | Jul 25, 2023 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/6889
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formulaeLAn-Z-X—WwD and BZ-X—WwDwherein: D is a drug moiety; L is a ligand; B is a blocking group; A is an optional acyl unit; Z is an amino acid or a peptide residue; X is an aminobenzyl ether self-immolative spacer group; W is an optional second self-immolative group; n is an integer of 0 or 1; and w is an integer of 0 or 1, and compositions of said compounds with pharmaceutically acceptable carrier, diluent and/or excipient, and methods of delivery the drug D via the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.